A REVIEW OF ONOLIDINE

Epidural clonidine applied being an adjunct to neighborhood anesthetics has 3 unique mechanisms of action. 1st, the stimulation of alpha-2-receptors within the dorsal horn decreases ache transmission. Next, clonidine may cause area vasoconstriction that limits vascular elimination of local epidural anesthetics.Clonidine is an extended-expression me